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Clinical-Grade Formulas

TEMPERED™
BY BUILT DIFFERENT™

Co-formulated with Ortho Molecular Products. Practitioner-grade foundations for men over 40 who demand the same standard from their supplements as they do from their training.
Ortho Molecular Co-Formulation
Third-Party Tested
GMP Certified
Non-GMO
Free US Shipping $100+
30-Day Guarantee
Seven Formulas

ONE STANDARD.
NO COMPROMISES.

Each formula does one job, exceptionally well. Tap any card to see exactly what's inside.

Foundation Formula
Foundation
FOUNDATION
MitoCore® Formula · 60 Capsules
Recharges cellular energy production. A full-spectrum multivitamin built around mitochondrial support — methylated B-vitamins, NAC, Acetyl L-Carnitine, and R-Lipoic Acid.
60 Caps · 2-4/day
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Daily Essential
Omega
OMEGA
Orthomega® 820 · 60 Soft Gels
Supports cardiovascular health and blood sugar metabolism. 950mg of triglyceride-form omega-3s per soft gel — concentrated EPA and DHA.
60 Soft Gels · 1/day
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Frame
FRAME
K-Force® Formula · 60 Capsules
Promotes optimal bone health. High-dose D3 (5,000 IU) paired with MenaQ7® K2 — the ratio that drives calcium to your bones, not your arteries.
60 Caps · 1/day
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Rest
REST
Reacted Magnesium · 60 Capsules
Promotes muscle relaxation and energy production. Triple-source Albion® chelated magnesium — absorbed up to 8.8x better than the magnesium oxide most brands use.
60 Caps · 2/day
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Daily Biotic
DAILY BIOTIC
Ortho Biotic® Formula · 30 Capsules
Helps maintain gastrointestinal balance. 20 billion CFU across six clinically studied strains plus S. boulardii. Dairy-free.
30 Caps · 1/day
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Prime
PRIME
Creatine Monohydrate · 450g Powder
Enhances muscular performance, endurance and recovery. The most studied compound in sports nutrition — increasingly backed for cognitive performance and healthy aging too.
450g · 1 scoop/day
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Flagship Formula
Drive
DRIVE
Testosterone Support Complex · 120 Capsules
Supports healthy testosterone levels and free testosterone availability. Five clinically studied actives, three pathways, one system. See the science →
120 Caps · 2-4/day
View Product →
The Story Behind Tempered™

WHY THESE EXIST

These didn't come easy.

The formulas I trusted sat behind a practitioner channel. The kind you only reach through a medical provider. Most people never get near them.

I'm fortunate. My wife, Kristen Hanenian, APRN, AGNP-C, ABAAHP, is a double board certified nurse practitioner and the founder of Elite Medical. Functional, regenerative, and aesthetic medicine. Hormone optimization, peptides, advanced therapies. Her work helps people reach real health without giving up the way they want to look and feel.

Her practice is the door. It's how these come through under our own name.

That's the only reason you're looking at them right now.

TEMPERED™ is built to professional standards by Ortho Molecular. No fillers. No hidden blends.

This is the standard we hold every day. Now it's on your shelf at home.

— Keith Hanenian, Founder
Flagship Formula

DRIVE

“Support the System. Restore the Signal.”

Testosterone levels in men today are measurably lower than a generation ago — a decline documented in long-running clinical research (Travison et al., 2007) and accelerated by chronic stress, poor sleep, excess body fat, and micronutrient gaps. Most formulas address one piece of that picture. DRIVE was built around the full system.

Supports Healthy Testosterone Levels and Free Testosterone Availability Promotes Vitality, Energy and Physical Performance Helps Maintain Normal Stress Hormone Balance Supports Reproductive Health, Libido and Sperm Parameters Maintains Balanced Testosterone Metabolism
20-25%
of adult men have total testosterone levels below commonly used clinical thresholds

THREE SYSTEMS. ONE FORMULA.

Most testosterone formulas focus on stimulation alone. DRIVE takes a systems-based approach — addressing production, stress signaling, and downstream metabolism together.

Production

HPG AXIS

The hypothalamic-pituitary-gonadal axis drives testosterone production — GnRH triggers LH release, which signals the testes to produce testosterone.

Stress

HPA AXIS

Chronic cortisol elevation suppresses GnRH and LH and impairs the cells that produce testosterone. Stress is the silent saboteur of hormonal health.

Metabolism

DOWNSTREAM PATHWAYS

Even with adequate production, elevated SHBG binds testosterone and aromatase converts it to estradiol — reducing the free testosterone you actually have available.

FIVE ACTIVES. ONE SYSTEM.

Every ingredient at a clinically studied dose — not a sprinkle for the label. Tap any active to see the mechanism and the research behind it.

Tongkat Ali
LJ100® · 400mg
+

Supports endogenous testosterone production via HPG-axis signaling and cortisol reduction.

Clinical research on LJ100® (Talbott et al., 2013, J Int Soc Sports Nutr) studied 63 moderately stressed adults over 4 weeks and found increased testosterone alongside reduced cortisol.

Ashwagandha
1.5% Withanolides · 600mg
+

Adaptogenic cortisol reduction — removes stress-driven suppression of the HPG axis.

Research on standardized ashwagandha (Chauhan et al., 2022, Health Science Reports) followed 50 men with low libido over 8 weeks and found increases in testosterone alongside improved stress markers.

Fenugreek
Seed Extract · 500mg
+

Modulates aromatase and 5α-reductase activity, helping keep testosterone in its active form.

A 12-week study on standardized fenugreek (Rao et al., 2016, The Aging Male) in 120 men aged 43-70 found increases in total and free testosterone and improved sexual function scores.

Zinc
Albion® Bisglycinate Chelate · 10mg
+

A structural cofactor for 17β-hydroxysteroid dehydrogenase, an enzyme required for testosterone synthesis.

Research (Prasad et al., 1996, Nutrition) found that correcting zinc deficiency restored testosterone to normal physiological levels.

Boron
Albion® Bororganic Glycine · 6mg
+

Reduces SHBG to increase free testosterone availability and supports a favorable testosterone-to-estrogen ratio.

Research on daily boron supplementation (Naghii et al., 2011, J Trace Elem Med Biol) found favorable shifts in free testosterone and T:E2 ratio in healthy men.

SUGGESTED USE

2-4 capsules per day or as recommended by your health care professional.

KEY ADVANTAGES

  • No dependency risk — fully reversible, no endogenous suppression
  • Preserves fertility — does not suppress spermatogenesis
  • Addresses root causes — stress physiology, HPG signaling, and free hormone availability
  • Systems-based approach, not single-pathway stimulation
Shop Drive →

Available in a 120 capsule size. † These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

The Formulation

CLINICAL
GRADE.
ZERO
COMPROMISE.

Ortho Molecular Products has supplied licensed medical professionals for 35+ years. These formulas are not available in retail. Until now.

Every ingredient is at a clinically relevant dose. Methylated B vitamins. Chelated minerals. Re-esterified triglyceride omega-3. The gold standard forms that most brands skip because they cost more to produce.

35+
Years Ortho Molecular
3rd
Party Tested
GMP
Certified Facility
0
Fillers or Binders
Supplement Facts Label
Label Transparency
View Full Supplement Facts →
Ingredient Transparency

SUPPLEMENT FACTS

Every ingredient. Every dose. Nothing hidden. Taken directly from the official label.

Cellular EnergyImmune FunctionAntioxidant ProtectionDetoxification
Why It Works

Every cell runs on ATP made inside the mitochondria — and that output drops under poor sleep, chronic stress, and age. Foundation pairs a full B-vitamin and chelated mineral backbone with three antioxidants studied specifically for mitochondrial support: Acetyl L-Carnitine (shown to boost fatty-acid fuel flow into the mitochondria), N-Acetylcysteine (raises the body's master antioxidant, glutathione), and R-Lipoic Acid (recharges vitamin C, vitamin E, and CoQ10). Green tea extract, broccoli seed extract, and resveratrol round it out as plant compounds studied for shielding the mitochondria from everyday oxidative damage.

Research note: studies combining Acetyl L-Carnitine with R-Lipoic Acid have found measurably lower oxidative stress markers than either ingredient taken alone.

Supplement Facts
Serving Size: 4 Capsules
Servings Per Container: 15
Amount Per Serving% Daily Value
Vitamin A (from 5,000 IU Natural Beta Carotene)1,500 mcg   167%
Vitamin C (as Ascorbic Acid USP)100 mg   111%
Vitamin D (D3 as Cholecalciferol)25 mcg (1,000 IU)   125%
Thiamin (Vitamin B1, as Thiamine HCl USP)15 mg   1,250%
Riboflavin (Vitamin B2 USP)15 mg   1,154%
Niacin (as Niacinamide USP)15 mg   94%
Vitamin B6 (as Pyridoxine HCl USP)15 mg   882%
Folate (from 800 mcg as Quatrefolic®)1,360 mcg DFE   340%
Vitamin B12 (as Methylcobalamin)250 mcg   10,417%
Biotin50 mcg   167%
Pantothenic Acid (as d-Calcium Pantothenate USP)15 mg   300%
Calcium (as Dicalcium Malate, Albion®)75 mg   6%
Iodine (from Potassium Iodide)37 mcg   25%
Magnesium (as DiMagnesium Malate, Albion®)75 mg   18%
Zinc (as Zinc Bisglycinate Chelate, Albion®)5 mg   45%
Choline (as Choline Bitartrate)15 mg   3%
Manganese (as Manganese Bisglycinate Chelate, Albion®)1 mg   43%
Chromium (as O-polynicotinate, ChromeMate®)50 mcg   143%
Selenium (as Selenium Glycinate, Albion®)75 mcg   136%
Sodium20 mg   1%
N-Acetyl-L-Cysteine USP600 mg   *
Acetyl L-Carnitine HCl (MitoCarn®)500 mg   *
Malic Acid (as DiMagnesium Malate, Dicalcium Malate, Albion®)215 mg   *
Alpha Lipoic Acid (as R-Lipoic Acid)200 mg   *
Green Tea Leaf Extract (45% EGCg)45 mg   *
Brassica oleracea Seed Extract (13% Glucoraphanin)40 mg   *
trans-Resveratrol (from Polygonum cuspidatum)10 mg   *
Vitamin K2 (as MK-7, MenaQ7®)45 mcg   *
* Daily Value not established.
Other Ingredients: Hypromellose (Natural Vegetable Capsules), Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide.
WARNING: All forms of Vitamin K may interact with blood thinning medications. If you are taking such medicines, please consult your physician before taking this product.
Cardiovascular HealthBlood Sugar MetabolismCognitive FunctionInflammatory Balance
Why It Works

Most fish oil on the market is sold as an "ethyl ester" — cheaper to produce, but a structure your digestive enzymes weren't built to break down efficiently. Omega uses the triglyceride form instead, the same structure naturally found in fish, so it absorbs the way your body expects. Each soft gel also carries DPA, an intermediate fatty acid most fish oils skip — research suggests it acts as a reserve your body draws on to replenish both EPA and DHA over time.

Research note: studies have linked each additional gram of daily omega-3 intake to measurably improved blood pressure readings within the normal range.

Supplement Facts
Serving Size: 1 Soft Gel Capsule
Servings Per Container: 60
Amount Per Serving% Daily Value
Calories15
Total Fat1.5 g   2%
Cholesterol<5 mg   <2%
Total Omega-3s (as Triglycerides)950 mg   **
EPA (Eicosapentaenoic Acid)430 mg   **
DHA (Docosahexaenoic Acid)390 mg   **
Omega-3s (additional)130 mg   **
DPA (Docosapentaenoic Acid)50 mg   **
* Percent Daily Values are based on a 2,000 calorie diet.
** Daily Value not established.
Ingredients: Fish Oil (anchovy, jack mackerel, mackerel, sardine) — Highly Refined and Concentrated Omega-3, Gelatin, Glycerin, Water (Purified), Natural Flavors, Natural Tocopherols, Rosemary Extract (Leaf), Ascorbyl Palmitate. Contains: Fish.
Allergen: Contains fish (anchovy, jack mackerel, mackerel, sardine). Consult your physician before use if you are on anticoagulant therapy or blood pressure medication. Keep out of reach of children.
Calcium BalanceBone HealthArterial ElasticityImmune Function
Why It Works

Calcium needs an escort. Without enough vitamin K, calcium can end up calcifying arteries instead of strengthening bone. Frame pairs a 180mcg dose of MenaQ7® K2 — the dose threshold where research shows meaningfully better outcomes than the lower doses most brands use — with 5,000 IU of D3, the two nutrients that work together to direct calcium where it actually belongs.

Research note: population studies comparing K2 intake found measurably better cardiovascular markers in those consuming more MK-7, and Japanese research tracking nattō consumption (a natural MK-7 source) found stronger bone health outcomes among frequent consumers.

Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving% Daily Value
Vitamin D (D3 as Cholecalciferol)125 mcg (5,000 IU)   625%
Vitamin K2 (as Menaquinone-7, MenaQ7®)180 mcg   *
* Daily Value not established.
Other Ingredients: Microcrystalline Cellulose, Hypromellose (Natural Vegetable Capsule), Turmeric (color), Magnesium Stearate, Silicon Dioxide, Stearic Acid.
WARNING: All forms of Vitamin K may interact with blood thinning medications. If you are taking such medicines, please consult your physician before taking this product.
Cardiovascular SupportBlood PressureMuscle RelaxationEnergy Production
Why It Works

Most magnesium supplements use one cheap, poorly absorbed source — magnesium oxide or carbonate — which is exactly why they cause stomach issues and don't move the needle. Rest uses three Albion® chelated forms (malate, citrate, and glycinate) that each rely on a different absorption pathway, so you're not maxing out one route before the rest goes unused. More than half of Americans fall short of the recommended daily magnesium intake — and the gap widens with alcohol, caffeine, soda, and chronic stress, all of which deplete it further.

Research note: independent lab comparisons found Albion®'s chelated magnesium absorbed up to 8.8x better than magnesium oxide and 5.6x better than magnesium sulfate — the forms most low-cost magnesium products are built on.

Supplement Facts
Serving Size: 2 Capsules
Servings Per Container: 30
Amount Per Serving% Daily Value
Magnesium (as DiMagnesium Malate, Magnesium Citrate USP, Magnesium Lysinate Glycinate Chelate, Albion®)235 mg   56%
Other Ingredients: Hypromellose (Natural Vegetable Capsules), Stearic Acid, Magnesium Stearate.
Gastrointestinal BalanceGut ImmunityBowel RegularityMicronutrient Absorption
Why It Works

A capsule full of live bacteria only helps if the bacteria survive the trip through stomach acid. Daily Biotic uses a freeze-dried encapsulation process that keeps all six strains plus S. boulardii dormant — and protected — until they reach the gut, where moisture triggers them back to life. Each strain was selected for a specific, studied job: adhering to the intestinal wall, competing against harmful bacteria, and supporting the gut's immune signaling.

Research note: one of the included strains, L. rhamnosus (GG), has been shown in research to influence the activity of over 1,700 immune and inflammatory genes when taken at a sufficient dose.

Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 30
Amount Per Serving% Daily Value
Proprietary Blend (20 Billion CFU‡)133 mg   *
Lactobacillus acidophilus (La-14)*
Bifidobacterium bifidum (Bb-06)*
Lactobacillus rhamnosus (GG)*
Lactobacillus paracasei (Lpc-37)*
Bifidobacterium lactis (Bl-04)*
Lactobacillus plantarum (Lp-115)*
Saccharomyces boulardii200 mg (3 Billion CFU‡)   *
* Daily Value not established. ‡ Colony Forming Units.
Other Ingredients: Microcrystalline Cellulose, Hypromellose (Natural Vegetable Capsule), Silicon Dioxide, Magnesium Stearate. Dairy free.
CAUTION: This product contains a desiccant. Keep the desiccant in the bottle until all contents are consumed. Do not eat desiccant. Keep out of reach of children.
Muscular PerformanceLean Body MassHealthy AgingCognitive Function
Why It Works

About two-thirds of your muscle's creatine is stored as phosphocreatine — the reserve your body taps first to regenerate ATP during short, hard efforts. More reserve means more reps before you run out of gas. Past the gym, the same energy system applies to your brain: neurons rely on the same phosphocreatine pathway under cognitive load, and creatine combined with resistance training has shown real promise for preserving muscle and bone in the exact decades this stack is built for.

Research note: a 2024 study found a single dose of creatine improved reaction time and working memory in sleep-deprived adults — a benefit previously thought to require months of consistent use. Separately, a meta-analysis of adults over 50 found creatine users averaged roughly 3 lbs more lean mass gain over 12-24 weeks of training versus non-users.

Supplement Facts
Serving Size: 1 Scoop (5 Grams)
Servings Per Container: About 90
Amount Per Serving% Daily Value
Creatine Monohydrate5 g   *
* Daily Value not established.
Mix 1 scoop (5g) with 8 ounces of water or your preferred beverage per day.
Supplement Facts
Serving Size: 4 Capsules
Servings Per Container: 15
Amount Per Serving% Daily Value
Zinc (as Zinc Bisglycinate Chelate, Albion®)10 mg   91%
Ashwagandha Root Extract (1.5% Withanolides)600 mg   *
Fenugreek (Trigonella foenum-graecum) Seed Extract500 mg   *
Tongkat Ali (Eurycoma longifolia) Root Extract (LJ100®)400 mg   *
Boron (as Bororganic Glycine, Albion®)6 mg   *
* Daily Value not established.
Other Ingredients: Microcrystalline Cellulose, Hypromellose (Natural Vegetable Capsules), Magnesium Stearate, Silicon Dioxide.
Do not consume this product if you are pregnant or nursing. Available in a 120 capsule size. Consult your physician for further information.
Common Questions

EVERYTHING
YOU NEED TO KNOW

The Ortho Molecular formulations use highly bioavailable forms that are generally well-tolerated. However, always review any new supplement with your prescribing doctor, particularly if you are on blood thinners, statins, hormone therapy, or other medications. Vitamin K2 can interact with anticoagulants. Omega-3s may affect platelet aggregation at high doses. We are not a substitute for medical advice.

Ortho Molecular Products has supplied licensed healthcare practitioners for over 35 years. Their formulations use clinical doses of the most bioavailable ingredient forms. These are not ingredients chosen for cost. They are chosen for efficacy. Most retail supplements use cheap forms at sub-clinical doses to hit a price point. We do not.

Most men notice improved energy within 2-4 weeks of starting Foundation. Frame typically shows its full benefit on D3 and K2 status in 6-8 weeks. Omega's cardiovascular and metabolic benefits build over 8-12 weeks of consistent use. These are foundational formulas - they work best taken daily, consistently.

Yes. All Built Different supplements are manufactured in a GMP-certified facility and undergo third-party testing for purity, potency, and contaminants. What is on the label is what is in the capsule, at the dose stated, with no hidden fillers or undisclosed additives.

We stand behind every formula with a 30-day satisfaction guarantee. If you are not satisfied within 30 days of purchase, contact us for a full refund. Opened products are accepted. No questions asked.

Verified Reviews

REAL MEN.
REAL RESULTS.

4.9
Based on 47 reviews
Drive - 8 Weeks

"My doctor asked what changed after 8 weeks. More importantly, I felt it - energy, drive, recovery between sessions. These are clinical-quality formulas. I am not taking anything else."

David K.
Age 58 - Houston, TX
Foundation - 12 Weeks

"Energy noticeably better within 3 weeks. I have been taking supplements for 20 years and never noticed much. The methylated B vitamins make a real difference. This is not a retail formulation."

James R.
Age 52 - Dallas, TX
Omega - 8 Weeks

"No fish burp. Zero. I have tried six different omega supplements and they all taste like fish. Omega has no aftertaste whatsoever. The triglyceride form makes that difference."

Mark T.
Age 49 - Phoenix, AZ
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Legal & Health Disclaimers +

Dietary Supplement DisclaimerTEMPERED™ products are dietary supplements. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Health DisclaimerInformation on this site is for general informational purposes only and is not medical advice or a substitute for care from a qualified healthcare professional. Consult your physician before starting any supplement, especially if pregnant, nursing, taking medication, or managing a health condition. Some TEMPERED™ formulas contain Vitamin K, which can interact with blood thinning medication.

Earnings DisclaimerAny income or results statements referenced on this site (including on our affiliate program pages) are illustrative and not a guarantee of earnings. Individual results depend on effort, audience, and promotional activity.

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